News Medical

Insight into the Different Clinical Trial Study Designs

Clinical trials are well-controlled and designed experiments that aim to prove that an Investigational Medicinal Product (IMP) is effective. Clinical trial data is submitted to the national health ...

Tvardi Therapeutics’ TTI-109 Phase 1 Study Confirms Prodrug Design, Improved Tolerability and Pharmacodynamic Evidence of STAT3 Target Engagement

TTI-109 delivered TTI-101-equivalent exposure with improved tolerability and meaningful reductions in disease-relevant STAT3-driven immune cell ...
ascopubs.org

Performance of Two-Phase Designs for the Time-to-Event Outcome and a Case Study Assessing the Relapse Risk Associated With B-ALL Subtypes

As biomarker studies employ increasingly complex and expensive genomics and other correlative methods, it is increasingly important to rigorously design these studies and analyze the downstream ...
Forbes

Jay Bhattacharya Called Test-Negative Study Design ‘Crap.’ Here’s How We Know Whether Vaccines Measured With It Are Effective

WASHINGTON, DC - MARCH 5: Jayanta Bhattacharya, U.S. President Donald Trump's nominee to be Director of the National Institutes of Health, speaks at his confirmation hearing before the Senate ...