The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

When AlphaFold solved the protein-folding problem in 2020, it showed that artificial intelligence could crack one of biology’s deepest mysteries: how a string of amino acids folds itself into a ...

The accumulation of mutations in DNA is often mentioned as an explanation for the aging process, but it remains just one hypothesis among many. A team from the University of Geneva (UNIGE), in ...

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins—yet it exists in large quantities. A research team from ...

A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or so-called 'junk' DNA—includes many of the "switches" that control when and ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

Using STING-seq, short for systematic targeting and inhibition of noncoding GWAS loci with single cell sequencing, Sanjana and his team identified promising sequence variants linked to various ...