However,instead of attacking cancer cells, they are typically co-opted to support tumor growth, metastasis, and therapeutic ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Significant opportunities in the cancer metabolism-based therapeutics market include leveraging precision medicine to target unique cancer cell metabolic pathways, driving personalized treatment ...

Metabolic reprogramming is a defining hallmark of breast cancer, encompassing diverse alterations in energy utilisation, biosynthetic pathways and intracellular signalling. Tumour cells frequently ...

Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...

AbstractNon apoptotic cell death programs particularly ferroptosis and cuproptosis are transforming how we understand cancer ...

Tumor-associated macrophages (TAMs) are immune cells that tumors hijack to fuel their own growth and evade immune attack. A ...

Aerobic glycolysis dominates lesion bioenergetics, with lactate promoting histone lactylation, M2 macrophage polarization, CD8⁺ T-cell exhaustion, EMT, and fibrosis that reinforce immune-protected ...

Breast cancer development is not solely the result of cancer cells acting independently, it involves a dynamic and complex ecosystem composed of cancer cells, immune cells, fibroblasts, adipocytes, ...

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently ...

Leuven, 11 March 2025 – Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center ...