Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which garnered a Nobel Prize in 1953, brought into clear view structures inside ...

In this episode of C&EN Uncovered, host Craig Bettenhausen speaks with C&EN senior editor Laurel Oldach about a laser phase ...

Researchers have introduced a solution to the problem of light-sheet fluorescence microscopy: novel illumination beams designed based on deep learning using a trainable phase mask. Their study ...

(A) When a traditional Gaussian beam is used, diffraction causes the illumination beam to widen at the edges. (B) Joint optimization scheme. A network predicts the positions of beads in the focal ...