Backed by new research findings, researchers at the UNC School of Medicine have developed a new reporting system that will allow researchers across the United States to confirm the genetic accuracy of ...

In biomedical research using mouse models, preparing pseudopregnant recipient females is a standard step in embryo transfer ...

In the world of biomedical research, the humble lab mouse is a superstar—it’s easy enough to rear in large quantities, shares a considerable amount of core biological processes with humans, and is ...

When laboratory mice step out of their plastic cages and into real soil, their behavior changes so dramatically that it forces a rethink of what stress, health and even “normal” really mean. The story ...

Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19. According to their new study in ...

A fundamental challenge in preclinical research is accurately predicting human responses using conventional animal models. Traditional approaches often fail to adequately model human disease, creating ...

One of those genes encodes the enzyme DHDDS, part of the pathway that glycosylates proteins in higher cells. Retinitis pigmentosa from DHDDS mutations is called RP59. This is a recessive genetic ...

In the wild, a mouse or rat leads a precarious life. In the city, they dodge traps, poisons, and broom-wielding humans. In the countryside, they face owls, shotguns, and more poison. As Australia’s ...

Vision changes are an inevitable part of aging, but why are some more susceptible to age-related eye diseases and why do some individuals experience more severe decline than others? New research from ...

Scientists have conducted important research ...