Although tablet manufacture is traditionally a batchbased wet granulation process, there are many advantages to be gained by adopting dry granulation, including lower costs and increased yields.

The authors review developments in wet granulation using a twin-screw extruder. As a result of changing philosophies towards continuous manufacturing, new equipment is being introduced into ...

Dry granulation, also called roller compaction, has been a popular method in recent years and has many applications. The powder is compressed between revolving rollers to generate flakes. The flakes ...